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Practical Issues in Wound, Skin and Ostomy Management
Our skin provides a natural barrier to the environment. This is crucial for our health, as skin protects us from invasive pathogens such as bacteria and viruses. (more…)
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Physicians evaluate new device to test for cervical cancer. Comparison of Tissue Yield Using Frictional Fabric Brush Versus Sharp Curettage For Endocervical Curettage.
Women undergoing cervical biopsies might have lower odds of repeat tests with a rotating fabric brush than a sharp instrument because the soft device may capture more cells for analysis, a recent study suggests. Furthermore, biopsies with the softer tool may be less painful, researchers say. Cervical biopsies sometimes fail to collect enough cells from the cervix to accurately test for cancer, in which case another biopsy is needed. (more…)
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Investigators at the University of California in San Francisco are recruiting people with MS for an international study of the gut microbiome – the population of bacteria in the gut – in MS. They are seeking people with primary progressive MS nationwide (there is no need for onsite visits), as well as people with any other type of MS who can make a one-time visit to San Francisco, New York, Boston or Pittsburgh. The overall purpose of these studies is to investigate the potential role of gut bacteria in MS.
Safety and Efficacy Study of VM202 in the Treatment of Chronic Non-Healing Foot Ulcers. This study will assess the safety and efficacy of using gene therapy via intramuscular injections of the calf for patients with chronic non-healing foot ulcers.
The first patient has been dosed in a Phase III trial assessing ViroMed’s VM202, the first pivotal study of a gene therapy indicated for patients with nonhealing diabetic foot ulcers (NHU) and concomitant peripheral artery disease (PAD).
The Phase III trial (NCT02563522) is a double-blind, placebo-controlled, multicenter study designed to evaluate VM202 for safety and efficacy in 300 adults with a diabetic foot ulcer and concomitant PAD. Two hundred patients will be randomized to VM202 and the other 100 to placebo, ViroMed’s U.S. division VM BioPharma said yesterday. (more…)
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Scientists at Ohio State University have developed a new method that has the capability of changing the body’s existing cells into new cells to promote healing. The method, called Tissue Nanotransfection (TNT), reprograms cells through a device that uses nanotechnology. The way it would work: First, doctors would apply a light electrical stimulation to the surface of the skin. They would then place a small chip about the size of a cuff link onto the site of the wound. In less than a second, this chip would deliver reprogramming factors (pre-programmed DNA or RNA) non-invasively into living skin cells via a high-intensity, focused electric field, converting them into whatever type of cells a scientist or doctor may choose. (more…)
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AlloSource, one of the nation’s largest providers of cartilage, bone, skin, soft-tissue, and cellular allografts to advance patient healing in surgical procedures and wound care, today announced the release of AlloFuse® Select CM, a premium addition to AlloSource’s AlloFuse portfolio. (more…)
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A new patient resource has launched in the UK offering primary care healthcare professionals (HCPs) the opportunity to help patients self-care for their wounds and minimise scarring.
The new patient booklet resource, ‘Supporting you to care for wounds and to minimise scarring’, created with help from expert Dermatologist, Justine Hextall, and supported by Bio-Oil, has been developed following research demonstrating the the frequency that HCP’s are required to provide support to patients in primary care, with one in five (20%) being asked for advice on a weekly basis. (more…)
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Carol Emanuele beat cancer. But for the last two years, the Philadelphia woman has been fighting her toughest battle yet. She has an open wound on the bottom of her foot that leaves her unable to walk and prone to deadly infection.
In an effort to treat her diabetic wound, doctors at a clinic in Northeast Philadelphia have prescribed a dizzying array of treatments. Freeze-dried placenta. Penis foreskin cells. High doses of pressurized oxygen. And those are just a few of the treatment options patients face.
“I do everything, but nothing seems to work,” said Emanuele, 59, who survived stage 4 melanoma in her 30s. “I beat cancer, but this is worse.” (more…)
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Antibiotic overuse contributes to the problems of antibiotic resistance and healthcare acquired infections, such as Clostridium difficile. Antibiotic stewardship programs improve patient outcomes, reduce antimicrobial resistance, and save money. These programs are designed to ensure patients receive the right antibiotic, at the right dose, at the right time, and for the right duration. (more…)
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Research shows that a skin-graft harvesting system aids chronic wound recovery and reduces care costs by accelerating the healing process.
More than six million cases of chronic wounds cost $20 billion each year in the United States. Diabetic ulcers, pressure sores, surgical site wounds, and traumatic injuries to high-risk patients account for most wounds that won’t heal. (more…)
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Washington, D.C. — In a presentation to the American Chemical Society meeting, Ankit Agarwal, a postdoctoral researcher at the University of Wisconsin-Madison, described an experimental approach to wound healing that could take advantage of silver’s anti-bacterial properties, while sidestepping the damage silver can cause to cells needed for healing.
Silver is widely used to prevent bacterial contamination in wound dressings, says Agarwal, “but these dressings deliver a very large load of silver, and that can kill a lot of cells in the wound.” (more…)
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One of the most amazing things about the human body is its ability to repair itself. Lacerations, punctures, abrasions all heal with little or no care. Chronic wounds, those that persist day after day, are a small subset of wounds but they compose a troublesome minority. They include, but are not limited to, diabetic foot ulcers (DFU), venous leg ulcers (VLU), and pressure ulcers (colloquially known as bedsores). These represent the body’s failure to fix itself. (more…)
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