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Topical gel containing blood pressure drugs shown effective in healing chronic wounds

An international research team led by Johns Hopkins University School of Medicine is seeking approval from the FDA for a topical gel they have created from oral blood pressure pills that has shown to be effective in the healing of chronic skin wounds in mice and pigs. A report of the team’s findings have been published in the Journal of Investigative Dermatology. Read more.

via HopkinsMedicine.org

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UVA student invents a new type of five-layered wound technology

Ashwinraj Karthikeyan, a student in UVA’s School of Engineering and Applied Science, presented his invention, Phoenix-Aid – a new type of five-layered wound care technology set to revolutionize how chronic wounds are treated in developing countries and impoverished areas around the world, at the Collegiate Inventors Competition in November. Read more.

pc: Dan Addison, University Communications, UVA

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Bacterial biofilms, begone

bacterial biofilm

By some estimates, bacterial strains resistant to antibiotics — so-called superbugs — will cause more deaths than cancer by 2050.

Colorado State University biomedical and chemistry researchers are using creative tactics to subvert these superbugs and their mechanisms of invasion. In particular, they’re devising new ways to keep harmful bacteria from forming sticky matrices called biofilms — and to do it without antibiotic drugs. (more…)

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Salivary peptide promotes wound healing, research reveals

salivary peptide wound healing wca

A study published online in The FASEB Journal delves into the mystifying fact that wounds in your mouth heal faster and more efficiently than wounds elsewhere. Until now, it was understood that saliva played a part in the wound healing process, though the extent of its role was unknown. The study examined the effects of salivary peptide histatin-1 on angiogenesis (blood vessel formation), which is critical to the efficiency of wound healing. Researchers found that histatin-1 promotes angiogenesis, as well as cell adhesion and migration. (more…)

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Omentum flap as a salvage procedure in deep sternal wound infection

omentum flap procedure deep sternal wound infection wca

Introduction: Deep sternal wound infections (DSWIs) are rare but devastating complication after median sternotomy following cardiac surgery. Especially in the presence of artificial material or inadequate preliminary muscle flaps, the pedicled omentum flap is due to its immunological properties, the predetermined flap in salvage procedures. (more…)

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Slugs inspire a surgical bio glue

slug inspire surgical bio glue wca

Slugs secrete biological defensive mucus that has now inspired a new type of surgical glue, prepared by researchers. This “bio-glue” has three main properties, it can move with the body, it is incredibly strong and it can stick to wet surfaces. The results of this breakthrough are published this week in the journal Science. (more…)

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Could probiotics replace antibiotics in wound healing?

lactobacilli probiotics replace antibiotics wound healing

The microbiome is known to play a major role in gut health, but what about our skin? Billions of bacteria reside there, and the probiotic types may hold great potential to prevent infections during wound healing.

Our skin provides a natural barrier to the environment. This is crucial for our health, as skin protects us from invasive pathogens such as bacteria and viruses. (more…)

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Study shows link between prophylactic dressing use and reduction in pressure injury rates

prophylactic dressing pressure injury

A new study shows a clear association between the prophylactic use of five-layer foam sacral dressings and reductions in pressure injury rates. Specifically, the study looked at the prophylactic use of Mölnlycke’s Mepilex® Border Sacrum dressing in the acute care setting over a six-year period (2010-2015). (more…)

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