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Bacterial biofilms, begone

bacterial biofilm

By some estimates, bacterial strains resistant to antibiotics — so-called superbugs — will cause more deaths than cancer by 2050.

Colorado State University biomedical and chemistry researchers are using creative tactics to subvert these superbugs and their mechanisms of invasion. In particular, they’re devising new ways to keep harmful bacteria from forming sticky matrices called biofilms — and to do it without antibiotic drugs. (more…)

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Salivary peptide promotes wound healing, research reveals

salivary peptide wound healing wca

A study published online in The FASEB Journal delves into the mystifying fact that wounds in your mouth heal faster and more efficiently than wounds elsewhere. Until now, it was understood that saliva played a part in the wound healing process, though the extent of its role was unknown. The study examined the effects of salivary peptide histatin-1 on angiogenesis (blood vessel formation), which is critical to the efficiency of wound healing. Researchers found that histatin-1 promotes angiogenesis, as well as cell adhesion and migration. (more…)

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Omentum flap as a salvage procedure in deep sternal wound infection

omentum flap procedure deep sternal wound infection wca

Introduction: Deep sternal wound infections (DSWIs) are rare but devastating complication after median sternotomy following cardiac surgery. Especially in the presence of artificial material or inadequate preliminary muscle flaps, the pedicled omentum flap is due to its immunological properties, the predetermined flap in salvage procedures. (more…)

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Slugs inspire a surgical bio glue

slug inspire surgical bio glue wca

Slugs secrete biological defensive mucus that has now inspired a new type of surgical glue, prepared by researchers. This “bio-glue” has three main properties, it can move with the body, it is incredibly strong and it can stick to wet surfaces. The results of this breakthrough are published this week in the journal Science. (more…)

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Could probiotics replace antibiotics in wound healing?

lactobacilli probiotics replace antibiotics wound healing

The microbiome is known to play a major role in gut health, but what about our skin? Billions of bacteria reside there, and the probiotic types may hold great potential to prevent infections during wound healing.

Our skin provides a natural barrier to the environment. This is crucial for our health, as skin protects us from invasive pathogens such as bacteria and viruses. (more…)

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Study shows link between prophylactic dressing use and reduction in pressure injury rates

prophylactic dressing pressure injury

A new study shows a clear association between the prophylactic use of five-layer foam sacral dressings and reductions in pressure injury rates. Specifically, the study looked at the prophylactic use of Mölnlycke’s Mepilex® Border Sacrum dressing in the acute care setting over a six-year period (2010-2015). (more…)

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Cervical Biopsy more efficient, less painful via new method

Can new tool make cervical biopsy more efficient, less painful

Physicians evaluate new device to test for cervical cancer. Comparison of Tissue Yield Using Frictional Fabric Brush Versus Sharp Curettage For Endocervical Curettage.

Women undergoing cervical biopsies might have lower odds of repeat tests with a rotating fabric brush than a sharp instrument because the soft device may capture more cells for analysis, a recent study suggests. Furthermore, biopsies with the softer tool may be less painful, researchers say. Cervical biopsies sometimes fail to collect enough cells from the cervix to accurately test for cancer, in which case another biopsy is needed. (more…)

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Scientists Seek People with Primary Progressive MS and Other Forms of MS to Study Gut Bacteria

Volunteers are being sought for a major study to help determine how the gut microbiome can be used to treat multiple sclerosis, lupus, and other diseases.

Investigators at the University of California in San Francisco are recruiting people with MS for an international study of the gut microbiome – the population of bacteria in the gut – in MS. They are seeking people with primary progressive MS nationwide (there is no need for onsite visits), as well as people with any other type of MS who can make a one-time visit to San Francisco, New York, Boston or Pittsburgh. The overall purpose of these studies is to investigate the potential role of gut bacteria in MS.

Scientists Focus on Gut Flora for Future Treatments of Autoimmune Diseases

(more…)

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Nurses, Doctors and Hospitals use Google Glass

nurses doctors hospitals use google glass

For surgical collaboration; rural telemedicine, nurses and doctors at Hospitals use Google Glass. Indianapolis-based Hodei Technology is bringing Glass to hospitals in two different ways: as a tool for surgeons to teach, communicate, and collaborate (via a product called Ikasi) and, via a product called Gemini, as a new kind of telemedicine, which CEO Guy Mascaro describes as “first person point-of-view telepresence”.

A lot of people think Google Glass, the tech company’s experiment with augmented reality and wearable computing, died when the Glass Explorer program closed up shop in 2015. In fact, the technology has continued to find a home with enterprise applications, particularly in healthcare. (more…)

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Gene Therapy for Non-Healing Diabetic Foot Ulcers Starts Phase III Trial

Diabetic Foot Ulcers

Safety and Efficacy Study of VM202 in the Treatment of Chronic Non-Healing Foot Ulcers. This study will assess the safety and efficacy of using gene therapy via intramuscular injections of the calf for patients with chronic non-healing foot ulcers.

The first patient has been dosed in a Phase III trial assessing ViroMed’s VM202, the first pivotal study of a gene therapy indicated for patients with nonhealing diabetic foot ulcers (NHU) and concomitant peripheral artery disease (PAD).

The Phase III trial (NCT02563522) is a double-blind, placebo-controlled, multicenter study designed to evaluate VM202 for safety and efficacy in 300 adults with a diabetic foot ulcer and concomitant PAD. Two hundred patients will be randomized to VM202 and the other 100 to placebo, ViroMed’s U.S. division VM BioPharma said yesterday. (more…)

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