A 39-year-old woman presents to the ED with leg pain and fever. She initially noted redness and pain above her knee 2 weeks ago and was evaluated at an outside hospital. She completed a 10-day course of oral antibiotics for cellulitis. Over the last two days, she has had progressive leg swelling of her entire right thigh. The pain is now so severe that she is having difficulty walking. Her past medical history is negative for diabetes mellitus, chronic liver disease, or alcohol and IV drug use.
On exam, she is febrile to 102.7 F, heart rate is 96 bpm, and blood pressure is 112/65. She has a 12 cm area of faint erythema on her right thigh and tenderness to palpation of her entire right leg with diffuse edema. There is no ecchymosis or bullae formation. (more…)
MicroRNAs are interesting target structures for new therapeutic agents. They can be blocked through synthetic antimiRs. However, to date it was not possible to use these only locally. Researchers at Goethe University Frankfurt have now successfully achieved this in the treatment of impaired wound healing with the help of light-inducible antimiRs.
MicroRNAs are small gene fragments which bond onto target structures in cells and in this way prevent certain proteins from forming. As they play a key role in the occurrence and manifestation of various diseases, researchers have developed what are known as antimiRs, which block microRNA function. The disadvantage of this approach is, however, that the blockade can lead to side effects throughout the entire body since microRNAs can perform different functions in various organs. Researchers at Goethe University Frankfurt have now solved this problem. (more…)
The FDA-approved skin substitute reduces inflammation and transforms chronic wounds into acute injuries.
Six hours north of Reykjavik, along a narrow road tracing windswept fjords, is the Icelandic town of Isafjordur, home of 3,000 people and the midnight sun. On a blustery May afternoon, snow still fills the couloirs that loom over the docks, where the Pall Palsson, a 583-ton trawler, has just returned from a three-day trip. Below the rust-spotted deck, neat boxes are packed with freshly caught fish and ice. “If you take all the skins from that trawler,” says Fertram Sigurjonsson, the chairman and chief executive officer of Kerecis Ltd., gesturing over the catch, “we would be able to treat one in five wounds in the world.” (more…)
Washington, D.C. – The National Pressure Ulcer Advisory Panel (NPUAP) announced the convening of its subcommittee, the Support Surface Standards Initiative (S3I), this spring to approve new standards tests that may help prevent pressure injuries in bed-bound individuals. (more…)
PolarityTE (TM) Regenerates Full-Thickness Hair-Bearing Skin in Burns and Wounds Using Their Revolutionary Platform Technology. First ever known successful regeneration of full-thickness skin and hair; Company poised to initiate human trial in the third quarter of 2017; Management to host conference call Thursday, June 8th at 4:30pm ET.
Salt Lake City, UT — (Marketwired) — 06/08/17 — PolarityTE™, Inc. (NASDAQ: COOL) today announced pre-clinical results demonstrating that the Company’s lead product, SkinTE™, regenerated full-thickness, organized skin and hair follicles in third degree burn wounds. The findings represent the first known successful regeneration of skin and hair in full-thickness swine wound models, the standard animal model for human skin. The Company expects to initiate a human clinical trial evaluating the autologous homologous SkinTE™ construct in the third quarter of 2017. (more…)
A substance found in parasitic worms’ spit might help prevent thousands of amputations a year, scientists in north Queensland have said. James Cook University researchers in Cairns are harnessing the molecule produced by a Thai liver parasite that can “supercharge” the healing of wounds.
Australian Institute of Tropical Health and Medicine parasitologist Michael Smout said non-healing wounds were of particular concern for diabetics and smokers. Dr Smout said the parasite used the molecule to keep its host healthy and prolong its own life. “It’ll live for a decade or two, and it’s munching around your liver, and zipping up the wounds as it goes,” he said. (more…)
Bandages are intended to keep a dressing secure and clean in order to reduce healing time and infection rate. However, they may be about to get a new use-case, courtesy of a project from the United Kingdom’s Swansea University Institute of Life Science.
What researchers there have been working on is a new smart bandage capable of tracking how a wound is healing and sending that data back to doctors, via 5G technology. To do this it would employ tiny “nanosensors” able to fit comfortably within the fabric of regular bandages. (more…)
MIDDLETOWNThe Wound Care Center and Hyperbaric Services at Atrium Medical Center recently was recognized with a national award for clinical excellence.
The Center of Distinction Award was presented by Healogics, the nation’s leading and largest wound care management company. The center was also honored with the Healogics President’s Circle Award.
The awards recognize outstanding clinical outcomes for 12 consecutive months, including patient satisfaction higher than 92 percent, and a wound healing rate of at least 91 percent in less than 31 median days. (more…)
A glass-based wound care product that emerged from research by a doctoral student at Missouri University of Science and Technology has been approved by the U.S. Food and Drug Administration for human use and is now available on the commercial market.
Steve Jung laid the groundwork for the Mirragen Advanced Wound Matrix while earning a master’s degree in ceramic engineering and a Ph.D. in materials science and engineering at Missouri S&T. Jung is now chief technology officer at Mo-Sci Corp., a Rolla specialty glass manufacturer that continued the product’s development in collaboration with ETS Wound Care, also of Rolla. (more…)
Smart bandages which can detect how well a wound is healing and send a progress report to the doctor will be trialled within the next year, scientists have said. The dressings are fitted with tiny sensors which can pick up blood clotting, or spot infections, and wirelessly send data back to a clinician. Swansea University, which is hoping to trial the bandages within 12 months, said the new technology could offer a personalised approach to medicine.
Currently patients with wounds are advised to return to the doctor in a certain amount of time. But each case may need a longer time to heal, or may have become infected before the visit. (more…)
Laughlin Center for Wound Care and Hyperbarics has been honored as the Wound Care Center of the Year as well as recognized with a national award for continued excellence in wound healing by Healogics Inc., a wound care management company.
Leaders, physicians and clinicians from Laughlin Center for Wound Care and Hyperbarics recently gathered to celebrate the center’s receipt of the Robert A. Warriner III Center of Excellence award, according to a news release.
One of many dreaded tags from a Centers for Medicare & Medicaid Survey is F-Tag 314 — Pressure ulcers.
CMS writes, “Each resident must receive and the facility must provide the necessary care and services to attain or maintain the highest practicable physical, mental, and psychosocial well-being, in accordance with the comprehensive assessment and plan of care.” (more…)