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Practical Issues in Wound, Skin and Ostomy Management
Researchers at NYU’s Tandon School of Engineering have teamed up with those from the university’s Rory Meyers College of Nursing to develop a machine-learning algorithm that could help detect a lymphatic system disease before doctors are able to.
There is no cure for lymphedema, only physical exercises that can keep the symptoms in check. (more…)
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Washington, D.C. — In a presentation to the American Chemical Society meeting, Ankit Agarwal, a postdoctoral researcher at the University of Wisconsin-Madison, described an experimental approach to wound healing that could take advantage of silver’s anti-bacterial properties, while sidestepping the damage silver can cause to cells needed for healing.
Silver is widely used to prevent bacterial contamination in wound dressings, says Agarwal, “but these dressings deliver a very large load of silver, and that can kill a lot of cells in the wound.” (more…)
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One of the most amazing things about the human body is its ability to repair itself. Lacerations, punctures, abrasions all heal with little or no care. Chronic wounds, those that persist day after day, are a small subset of wounds but they compose a troublesome minority. They include, but are not limited to, diabetic foot ulcers (DFU), venous leg ulcers (VLU), and pressure ulcers (colloquially known as bedsores). These represent the body’s failure to fix itself. (more…)
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The new research has identified (see below) a peptide found from the Komodo dragon (Varanus komodoensis), called VK25, which appears to be useful as a cationic antimicrobial peptide (CAMP). There is currently considerable interest in antimicrobial peptides in a world where antibiotic effectiveness is in decline. These peptides are potent, broad spectrum antibiotics which demonstrate potential as novel therapeutic agents. (more…)
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Pennsylvania state trooper Matt Uram was talking with his wife at a July Fourth party in 2009 when a misjudged spray of gasoline burst through a nearby bonfire and set him alight. Flames covered the entire right side of his body, and after he fell to the ground to smother them, his wife beat his head with her bare hands to put out his burning hair. It was only on the way to the ER, as the shock and adrenaline began to wear off, that the pain set in. “It was intense,” he says. “If you can imagine what pins and needles feel like, then replace those needles with matches.” (more…)
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Although it is described as “one of society’s greatest achievements,” with the aging population, cancer incidence is expected to accelerate rapidly, as 50% of cancer occurs within this age group.(1)
Nutrition therapy is a crucial component of cancer care. Early and continuous nutrition management is necessary to avoid malnutrition, as this is associated with poor clinical outcomes.(2) Often, the elderly already face chronic comorbid conditions, such as high blood pressure, heart disease, lung disease, diabetes, kidney disease, bone disease and arthritis, further complicating their care.(3) (more…)
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The cutting-edge of wound care is a progressively flexible one, where textiles, foams, and films are applied to wound management technology with the goal of synergistic physiological function. These innately intuitive materials underpin the emerging medical solutions that practitioners and their patients are finding more effective than traditional wound care and closure methods. With an aging population more frequently seeking medical care and a surge in diabetes diagnoses, market analysts predict a continuing rise in demand for advanced wound care management products, fueling an annual industry growth rate of 6.4% over the next five years. (more…)
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Three registered nurses (RN) at Panhandle Home Health have passed the National Wound Care & Ostomy Certification Course & Exam (WCC) as part of Panhandle Home Health’s Wound Care Initiative, started in 2013 with a single WCC-certified RN, Cathy Reifer. In 2015, WISH (Women Investing in Shepherd) awarded their inaugural grant to a regional nonprofit, Panhandle Home Health. This grant of $26,250, along with additional private donations and grants, has allowed thirteen nurses to participate in the intensive, week-long training course. These RNs are prepared to provide specialized consultation and a unique supervisory level of clinical expertise in wound assessment and the specialized care involved for patients. Their training involves differentiation of wound types and the appropriate care; recognizing the effects of cancer, heart disease, diabetes, or COPD on wound healing; understanding care products and their implementation; wound-healing techniques; and patient education. (more…)
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A 39-year-old woman presents to the ED with leg pain and fever. She initially noted redness and pain above her knee 2 weeks ago and was evaluated at an outside hospital. She completed a 10-day course of oral antibiotics for cellulitis. Over the last two days, she has had progressive leg swelling of her entire right thigh. The pain is now so severe that she is having difficulty walking. Her past medical history is negative for diabetes mellitus, chronic liver disease, or alcohol and IV drug use.
On exam, she is febrile to 102.7 F, heart rate is 96 bpm, and blood pressure is 112/65. She has a 12 cm area of faint erythema on her right thigh and tenderness to palpation of her entire right leg with diffuse edema. There is no ecchymosis or bullae formation. (more…)
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MicroRNAs are interesting target structures for new therapeutic agents. They can be blocked through synthetic antimiRs. However, to date it was not possible to use these only locally. Researchers at Goethe University Frankfurt have now successfully achieved this in the treatment of impaired wound healing with the help of light-inducible antimiRs.
MicroRNAs are small gene fragments which bond onto target structures in cells and in this way prevent certain proteins from forming. As they play a key role in the occurrence and manifestation of various diseases, researchers have developed what are known as antimiRs, which block microRNA function. The disadvantage of this approach is, however, that the blockade can lead to side effects throughout the entire body since microRNAs can perform different functions in various organs. Researchers at Goethe University Frankfurt have now solved this problem. (more…)
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