New Approach to Wound Healing Easy on Skin, Tough on Bacteria

wound healing

Washington, D.C. — In a presentation  to the American Chemical Society meeting, Ankit Agarwal, a postdoctoral researcher at the University of Wisconsin-Madison, described an experimental approach to wound healing that could take advantage of silver’s anti-bacterial properties, while sidestepping the damage silver can cause to cells needed for healing.

Silver is widely used to prevent bacterial contamination in wound dressings, says Agarwal, “but these dressings deliver a very large load of silver, and that can kill a lot of cells in the wound.” (more…)

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How to benefit from electrical stimulation for the treatment of chronic wounds

Electrical Stimulation Therapy

One of the most amazing things about the human body is its ability to repair itself. Lacerations, punctures, abrasions all heal with little or no care. Chronic wounds, those that persist day after day, are a small subset of wounds but they compose a troublesome minority. They include, but are not limited to, diabetic foot ulcers (DFU), venous leg ulcers (VLU), and pressure ulcers (colloquially known as bedsores). These represent the body’s failure to fix itself. (more…)

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Dragon blood may help wounds heal faster

synthetic peptide heal komodo dragon

A new study has identified a peptide, derived from the Komodo dragon, called VK25, which can be synthesized and used as an antimicrobial peptide to promote wound healing.

The new research has identified (see below) a peptide found from the Komodo dragon (Varanus komodoensis), called VK25, which appears to be useful as a cationic antimicrobial peptide (CAMP). There is currently considerable interest in antimicrobial peptides in a world where antibiotic effectiveness is in decline. These peptides are potent, broad spectrum antibiotics which demonstrate potential as novel therapeutic agents. (more…)

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Innovative ‘Smart Scar-Care’ pad to create a ‘scar-less’ world

smart scar care pad by professor cecillia litsang

An innovative “Smart Scar-Care” pad which serves the dual functions of reinforcing pressure and occlusion has been designed by researchers to treat hypertrophic scars from burns, surgeries and trauma.

Compared with the traditional pressure pads and silicone gel sheets, “Smart Scar-Care” pad has the advantages of both.

It showed good performance in reducing pigmentation and vascularity, improving elasticity and preventing dehydration in a clinical trial. It is more durable and user-friendly compared with the traditional pad (polyethylene foam) as reported by the patients. This innovative design has won the Grand Award and Gold Medal with the Congratulations of Jury at the 45th International Exhibition of Inventions of Geneva, 2017. (more…)

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Severe Burn Victims May Soon Be Able to Regrow Hair-Bearing Skin

Regenerates Full-Thickness Hair-Bearing Skin in Burns and Wounds

PolarityTE (TM) Regenerates Full-Thickness Hair-Bearing Skin in Burns and Wounds Using Their Revolutionary Platform Technology. First ever known successful regeneration of full-thickness skin and hair; Company poised to initiate human trial in the third quarter of 2017; Management to host conference call Thursday, June 8th at 4:30pm ET.

Salt Lake City, UT — (Marketwired) — 06/08/17 — PolarityTE™, Inc. (NASDAQ: COOL) today announced pre-clinical results demonstrating that the Company’s lead product, SkinTE™, regenerated full-thickness, organized skin and hair follicles in third degree burn wounds. The findings represent the first known successful regeneration of skin and hair in full-thickness swine wound models, the standard animal model for human skin. The Company expects to initiate a human clinical trial evaluating the autologous homologous SkinTE™ construct in the third quarter of 2017. (more…)

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Wound-healing molecule found in parasitic worm could help prevent amputations

dr smout wound healing molecule parasitic worm

A substance found in parasitic worms’ spit might help prevent thousands of amputations a year, scientists in north Queensland have said. James Cook University researchers in Cairns are harnessing the molecule produced by a Thai liver parasite that can “supercharge” the healing of wounds.

Australian Institute of Tropical Health and Medicine parasitologist Michael Smout said non-healing wounds were of particular concern for diabetics and smokers. Dr Smout said the parasite used the molecule to keep its host healthy and prolong its own life. “It’ll live for a decade or two, and it’s munching around your liver, and zipping up the wounds as it goes,” he said. (more…)

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Wound care technology invented at S&T hits marketplace

Wound care technology invented at S&T

A glass-based wound care product that emerged from research by a doctoral student at Missouri University of Science and Technology has been approved by the U.S. Food and Drug Administration for human use and is now available on the commercial market.

Steve Jung laid the groundwork for the Mirragen Advanced Wound Matrix while earning a master’s degree in ceramic engineering and a Ph.D. in materials science and engineering at Missouri S&T. Jung is now chief technology officer at Mo-Sci Corp., a Rolla specialty glass manufacturer that continued the product’s development in collaboration with ETS Wound Care, also of Rolla. (more…)

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Wound Care Swagger

By: Nancy Morgan, RN, BSN, MBA, WOCN, WCC, CWCMS, DWC

I was thrilled to be asked to write a blog for Wound Care Advisor. They asked me to come up with a name for the blog. I thought it would be easy… NOT ! I found myself doing all this research on how to make up a good name that would be catchy and memorable. I reached out to all my wound care friends for ideas and started a long list of names. Every morning I would look at this list and add more. Then I said I had to STOP THE INSANITY! I had to refocus and asked myself… who are you writing the blog for? It’s for people like me! I am a nurse that is in love with wound care, I have been in this field for almost two decades—ouch! that just dated me. I started at bedside then moved to an educator role co-founding the Wound Care Education Institute where we have taught over 16,000 clinicians, spreading the knowledge of Wound Care so they can make a difference in their patients’ lives. I am that person that “gets the rush” every time I see a wound. (more…)

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Nutritional Supplements

BY: NANCY MORGAN, RN, BSN, MBA, WOCN, WCC, CWCMS, DWC
Wound healing and nutrition go hand in hand. Without adequate fluids, calories, and protein, wound healing can be delayed.

Protein is extremely important in wound healing. Patients with wounds require almost double the protein intake (1.2 to 1.5 g/kg/day) of those without wounds. All stages of wound healing require adequate protein. The basis of the human body structure, protein is responsible for making enzymes involved in wound healing, cell multiplication, and collagen and connective-tissue building. (more…)

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Hole-ier than Thou, Evidence Based Regardless of the Evidence

evidence based medicine

by Dr. Michael Miller

There are certain phrases that make the hair on the back of my neck stand up.  Someone telling me that they are a good Jew, a good Christian, a good Muslim or the ultimate in self serving lies, “I ONLY practice EVIDENCE BASED MEDICINE”.  People who are what they claim they are do not need to announce it.  A short conversation, watching them work, others opinions about them all answer the question before it is asked.  Like the RN who asked for a recent presentation on the true science behind NPWT (no, you don’t really understand it).  She made sure to tell me not only that she practiced only EVIDENCE BASED MEDICINE but then gave me several examples which incidentally had absolutely no scientific evidence (save for articles from lots of dabblers doing lots of crazy things to people and writing about them).  I am now awaiting her response as she may have to realize that her version of EVIDENCE BASED is no more real than Kim Kardashian’s celebrity. (more…)

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