WCA Archives - Page 3 of 37 - Wound Care Advisor

Gene Therapy for Non-Healing Diabetic Foot Ulcers Starts Phase III Trial

Safety and Efficacy Study of VM202 in the Treatment of Chronic Non-Healing Foot Ulcers. This study will assess the safety and efficacy of using gene therapy via intramuscular injections of the calf for patients with chronic non-healing foot ulcers.

The first patient has been dosed in a Phase III trial assessing ViroMed’s VM202, the first pivotal study of a gene therapy indicated for patients with nonhealing diabetic foot ulcers (NHU) and concomitant peripheral artery disease (PAD).

The Phase III trial (NCT02563522) is a double-blind, placebo-controlled, multicenter study designed to evaluate VM202 for safety and efficacy in 300 adults with a diabetic foot ulcer and concomitant PAD. Two hundred patients will be randomized to VM202 and the other 100 to placebo, ViroMed’s U.S. division VM BioPharma said yesterday. (more…)

Success as an HME compression provider takes commitment, education and an understanding that there is more to compression beyond the feet.

The compression sock is an integral product to carry for any HME provider committed to using compression technology to help patients. Compression doesn’t even need to be required due a medical condition – it’s an almost universal need. Sitting or standing for excessive amounts of time can be terrible for your health, especially the feet. For example, sitting with your legs crossed beneath your chair can cause pressure that results in swollen ankles or varicose veins. And standing all day at work can cause issues from your neck all the way to your feet. (more…)

Scars are a particularly sore subject for most people. Not only are they aesthetically unpleasing, but some of them can prove painful. That’s why research into minimizing the appearance of scars continues to be a central priority of wound care-related research. In the last several months alone, there have been quite a few exciting such breakthroughs. (more…)

Scientists at Ohio State University have developed a new method that has the capability of changing the body’s existing cells into new cells to promote healing. The method, called Tissue Nanotransfection (TNT), reprograms cells through a device that uses nanotechnology. The way it would work: First, doctors would apply a light electrical stimulation to the surface of the skin. They would then place a small chip about the size of a cuff link onto the site of the wound. In less than a second, this chip would deliver reprogramming factors (pre-programmed DNA or RNA) non-invasively into living skin cells via a high-intensity, focused electric field, converting them into whatever type of cells a scientist or doctor may choose. (more…)

ALLOFUSE® CORTICAL FIBERS & ALLOFUSE® FIBER BOAT

AlloFuse® Select CM – clinically proven to activate and support bone formation and can be used in a variety of spinal, neurologic, and orthopedic procedures.

AlloSource, one of the nation’s largest providers of cartilage, bone, skin, soft-tissue, and cellular allografts to advance patient healing in surgical procedures and wound care, today announced the release of AlloFuse® Select CM, a premium addition to AlloSource’s AlloFuse portfolio. (more…)

Minimize scarring through new patient booklet.

A new patient resource has launched in the UK offering primary care healthcare professionals (HCPs) the opportunity to help patients self-care for their wounds and minimise scarring.

The new patient booklet resource, ‘Supporting you to care for wounds and to minimise scarring’, created with help from expert Dermatologist, Justine Hextall, and supported by Bio-Oil, has been developed following research demonstrating the the frequency that HCP’s are required to provide support to patients in primary care, with one in five (20%) being asked for advice on a weekly basis. (more…)

Carol Emanuele beat cancer. But for the last two years, the Philadelphia woman has been fighting her toughest battle yet. She has an open wound on the bottom of her foot that leaves her unable to walk and prone to deadly infection.

In an effort to treat her diabetic wound, doctors at a clinic in Northeast Philadelphia have prescribed a dizzying array of treatments. Freeze-dried placenta. Penis foreskin cells. High doses of pressurized oxygen. And those are just a few of the treatment options patients face.

“I do everything, but nothing seems to work,” said Emanuele, 59, who survived stage 4 melanoma in her 30s. “I beat cancer, but this is worse.” (more…)

antibiotic overuse pressure injury infection

Antibiotic overuse contributes to the problems of antibiotic resistance and healthcare acquired infections, such as Clostridium difficile. Antibiotic stewardship programs improve patient outcomes, reduce antimicrobial resistance, and save money. These programs are designed to ensure patients receive the right antibiotic, at the right dose, at the right time, and for the right duration. (more…)

Researchers at NYU’s Tandon School of Engineering have teamed up with those from the university’s Rory Meyers College of Nursing to develop a machine-learning algorithm that could help detect a lymphatic system disease before doctors are able to.

There is no cure for lymphedema, only physical exercises that can keep the symptoms in check. (more…)

Research shows that a skin-graft harvesting system aids chronic wound recovery and reduces care costs by accelerating the healing process.

More than six million cases of chronic wounds cost $20 billion each year in the United States. Diabetic ulcers, pressure sores, surgical site wounds, and traumatic injuries to high-risk patients account for most wounds that won’t heal. (more…)

Crawford Healthcare, one of the biggest makers of advanced wound-care products in the UK, has won clearance from US regulators for a medical dressing that it says will “save limbs”.

The product, called KerraCel AG, soaks up fluid and bacteria from nasty, oozing wounds and locks it away as a gel. It is also the only dressing of its kind to contain silver at a special concentration to kill all bacteria – even those resistant to antibiotics – that prevent chronic wounds, such as diabetic ulcers and pressure sores, from healing. (more…)

Washington, D.C. — In a presentation to the American Chemical Society meeting, Ankit Agarwal, a postdoctoral researcher at the University of Wisconsin-Madison, described an experimental approach to wound healing that could take advantage of silver’s anti-bacterial properties, while sidestepping the damage silver can cause to cells needed for healing.

Silver is widely used to prevent bacterial contamination in wound dressings, says Agarwal, “but these dressings deliver a very large load of silver, and that can kill a lot of cells in the wound.” (more…)

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Tag: WCA

Gene Therapy for Non-Healing Diabetic Foot Ulcers Starts Phase III Trial

Compression Sock for Excessive Sitting or Standing

Doctors Find New Natural Way to Prevent Scars

A new way of healing wounds in the future discovered by scientists

AlloFuse® Select CM Supports Your Patient’s Healing

AlloFuse® Select CM – clinically proven to activate and support bone formation and can be used in a variety of spinal, neurologic, and orthopedic procedures.

Bio-Oil helps self-care for wounds

Minimize scarring through new patient booklet.

Wounds that won’t heal can be devastating

Antibiotic use in pressure injury infections

NYU docs are using machine learning to stop a stealthy disease before it’s too late

Better Skin Grafts – take only one layer

Crawford bags FDA clearance for wound dressing that will ‘save limbs’

New Approach to Wound Healing Easy on Skin, Tough on Bacteria