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Cervical Biopsy more efficient, less painful via new method

August 23, 2017February 25, 2020 Wound Care Advisor

Can new tool make cervical biopsy more efficient, less painful

Physicians evaluate new device to test for cervical cancer. Comparison of Tissue Yield Using Frictional Fabric Brush Versus Sharp Curettage For Endocervical Curettage.

Women undergoing cervical biopsies might have lower odds of repeat tests with a rotating fabric brush than a sharp instrument because the soft device may capture more cells for analysis, a recent study suggests. Furthermore, biopsies with the softer tool may be less painful, researchers say. Cervical biopsies sometimes fail to collect enough cells from the cervix to accurately test for cancer, in which case another biopsy is needed. (more…)

Scientists Seek People with Primary Progressive MS and Other Forms of MS to Study Gut Bacteria

August 23, 2017February 25, 2020 Wound Care Advisor

Volunteers are being sought for a major study to help determine how the gut microbiome can be used to treat multiple sclerosis, lupus, and other diseases.

Investigators at the University of California in San Francisco are recruiting people with MS for an international study of the gut microbiome – the population of bacteria in the gut – in MS. They are seeking people with primary progressive MS nationwide (there is no need for onsite visits), as well as people with any other type of MS who can make a one-time visit to San Francisco, New York, Boston or Pittsburgh. The overall purpose of these studies is to investigate the potential role of gut bacteria in MS.

Scientists Focus on Gut Flora for Future Treatments of Autoimmune Diseases

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Gene Therapy for Non-Healing Diabetic Foot Ulcers Starts Phase III Trial

August 20, 2017February 25, 2020 Wound Care Advisor

Safety and Efficacy Study of VM202 in the Treatment of Chronic Non-Healing Foot Ulcers. This study will assess the safety and efficacy of using gene therapy via intramuscular injections of the calf for patients with chronic non-healing foot ulcers.

The first patient has been dosed in a Phase III trial assessing ViroMed’s VM202, the first pivotal study of a gene therapy indicated for patients with nonhealing diabetic foot ulcers (NHU) and concomitant peripheral artery disease (PAD).

The Phase III trial (NCT02563522) is a double-blind, placebo-controlled, multicenter study designed to evaluate VM202 for safety and efficacy in 300 adults with a diabetic foot ulcer and concomitant PAD. Two hundred patients will be randomized to VM202 and the other 100 to placebo, ViroMed’s U.S. division VM BioPharma said yesterday. (more…)

Compression Sock for Excessive Sitting or Standing

August 8, 2017February 25, 2020 Wound Care Advisor

Success as an HME compression provider takes commitment, education and an understanding that there is more to compression beyond the feet.

The compression sock is an integral product to carry for any HME provider committed to using compression technology to help patients. Compression doesn’t even need to be required due a medical condition – it’s an almost universal need. Sitting or standing for excessive amounts of time can be terrible for your health, especially the feet. For example, sitting with your legs crossed beneath your chair can cause pressure that results in swollen ankles or varicose veins. And standing all day at work can cause issues from your neck all the way to your feet. (more…)

AlloFuse® Select CM Supports Your Patient’s Healing

August 7, 2017February 25, 2020 Wound Care Advisor

ALLOFUSE® CORTICAL FIBERS & ALLOFUSE® FIBER BOAT

AlloFuse® Select CM – clinically proven to activate and support bone formation and can be used in a variety of spinal, neurologic, and orthopedic procedures.

AlloSource, one of the nation’s largest providers of cartilage, bone, skin, soft-tissue, and cellular allografts to advance patient healing in surgical procedures and wound care, today announced the release of AlloFuse® Select CM, a premium addition to AlloSource’s AlloFuse portfolio. (more…)

Antibiotic use in pressure injury infections

August 3, 2017February 25, 2020 Wound Care Advisor

antibiotic overuse pressure injury infection

Antibiotic overuse contributes to the problems of antibiotic resistance and healthcare acquired infections, such as Clostridium difficile. Antibiotic stewardship programs improve patient outcomes, reduce antimicrobial resistance, and save money. These programs are designed to ensure patients receive the right antibiotic, at the right dose, at the right time, and for the right duration. (more…)

Dragon blood may help wounds heal faster

August 1, 2017February 25, 2020 Wound Care Advisor

A new study has identified a peptide, derived from the Komodo dragon, called VK25, which can be synthesized and used as an antimicrobial peptide to promote wound healing.

The new research has identified (see below) a peptide found from the Komodo dragon (Varanus komodoensis), called VK25, which appears to be useful as a cationic antimicrobial peptide (CAMP). There is currently considerable interest in antimicrobial peptides in a world where antibiotic effectiveness is in decline. These peptides are potent, broad spectrum antibiotics which demonstrate potential as novel therapeutic agents. (more…)

Meeting the nutritional needs of elderly cancer patients

August 1, 2017February 25, 2020 Wound Care Advisor

nutritional needs elderly cancer patients food vegetables apple

Although it is described as “one of society’s greatest achievements,” with the aging population, cancer incidence is expected to accelerate rapidly, as 50% of cancer occurs within this age group.(1)

Nutrition therapy is a crucial component of cancer care. Early and continuous nutrition management is necessary to avoid malnutrition, as this is associated with poor clinical outcomes.(2) Often, the elderly already face chronic comorbid conditions, such as high blood pressure, heart disease, lung disease, diabetes, kidney disease, bone disease and arthritis, further complicating their care.(3) (more…)

3 reasons why cornea is the new Glaucoma

July 28, 2017February 25, 2020 Wound Care Advisor

Ophthalmology is a great specialty partly because procedures, devices and drugs constantly evolve, keeping us learning and giving our patients better care. Ask your colleagues in other specialties, and you’ll find that the pace of change in most other medical fields is not nearly as rapid as in ours.

Over the past few years, this pace of change has been very evident in glaucoma, where minimally invasive procedures have greatly diminished the frequency of trabeculectomy and tube shunt procedures. In this issue of OSN, our cover story focuses on a specialty that’s now moving as quickly as glaucoma. And here are three reasons I believe cornea will continue to be the “next big thing” in eye care: (more…)

Three registered nurses pass National Wound Care course

July 17, 2017February 25, 2020 Wound Care Advisor

Three registered nurses (RN) at Panhandle Home Health have passed the National Wound Care & Ostomy Certification Course & Exam (WCC) as part of Panhandle Home Health’s Wound Care Initiative, started in 2013 with a single WCC-certified RN, Cathy Reifer. In 2015, WISH (Women Investing in Shepherd) awarded their inaugural grant to a regional nonprofit, Panhandle Home Health. This grant of $26,250, along with additional private donations and grants, has allowed thirteen nurses to participate in the intensive, week-long training course. These RNs are prepared to provide specialized consultation and a unique supervisory level of clinical expertise in wound assessment and the specialized care involved for patients. Their training involves differentiation of wound types and the appropriate care; recognizing the effects of cancer, heart disease, diabetes, or COPD on wound healing; understanding care products and their implementation; wound-healing techniques; and patient education. (more…)

Necrotizing Fasciitis: Pearls & Pitfalls

July 7, 2017February 25, 2020 Wound Care Advisor

A 39-year-old woman presents to the ED with leg pain and fever. She initially noted redness and pain above her knee 2 weeks ago and was evaluated at an outside hospital. She completed a 10-day course of oral antibiotics for cellulitis. Over the last two days, she has had progressive leg swelling of her entire right thigh. The pain is now so severe that she is having difficulty walking. Her past medical history is negative for diabetes mellitus, chronic liver disease, or alcohol and IV drug use.

On exam, she is febrile to 102.7 F, heart rate is 96 bpm, and blood pressure is 112/65. She has a 12 cm area of faint erythema on her right thigh and tenderness to palpation of her entire right leg with diffuse edema. There is no ecchymosis or bullae formation. (more…)

Wound healing in diabetic patients improved by Light-inducible antimiRs

July 7, 2017February 25, 2020 Wound Care Advisor

MicroRNAs are interesting target structures for new therapeutic agents. They can be blocked through synthetic antimiRs. However, to date it was not possible to use these only locally. Researchers at Goethe University Frankfurt have now successfully achieved this in the treatment of impaired wound healing with the help of light-inducible antimiRs.

MicroRNAs are small gene fragments which bond onto target structures in cells and in this way prevent certain proteins from forming. As they play a key role in the occurrence and manifestation of various diseases, researchers have developed what are known as antimiRs, which block microRNA function. The disadvantage of this approach is, however, that the blockade can lead to side effects throughout the entire body since microRNAs can perform different functions in various organs. Researchers at Goethe University Frankfurt have now solved this problem. (more…)

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