Wound-healing molecule found in parasitic worm could help prevent amputations

dr smout wound healing molecule parasitic worm

A substance found in parasitic worms’ spit might help prevent thousands of amputations a year, scientists in north Queensland have said. James Cook University researchers in Cairns are harnessing the molecule produced by a Thai liver parasite that can “supercharge” the healing of wounds.

Australian Institute of Tropical Health and Medicine parasitologist Michael Smout said non-healing wounds were of particular concern for diabetics and smokers. Dr Smout said the parasite used the molecule to keep its host healthy and prolong its own life. “It’ll live for a decade or two, and it’s munching around your liver, and zipping up the wounds as it goes,” he said. (more…)

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Smart bandage uses nanosensors to track how a wound is healing

smart bandage

Bandages are intended to keep a dressing secure and clean in order to reduce healing time and infection rate. However, they may be about to get a new use-case, courtesy of a project from the United Kingdom’s Swansea University Institute of Life Science.

What researchers there have been working on is a new smart bandage capable of tracking how a wound is healing and sending that data back to doctors, via 5G technology. To do this it would employ tiny “nanosensors” able to fit comfortably within the fabric of regular bandages. (more…)

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Smart bandages which tell doctor how wound is healing to begin trials

smart bandages

Smart bandages which can detect how well a wound is healing and send a progress report to the doctor will be trialled within the next year, scientists have said. The dressings are fitted with tiny sensors which can pick up blood clotting, or spot infections, and wirelessly send data back to a clinician. Swansea University, which is hoping to trial the bandages within 12 months, said the new technology could offer a personalised approach to medicine.

Currently patients with wounds are advised to return to the doctor in a certain amount of time. But each case may need a longer time to heal, or may have become infected before the visit. (more…)

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ETS Wound Care wins FDA nod for Mirragen wound matrix

ETS Wound Care

ROLLA, Mo.–(BUSINESS WIRE)–ETS Wound Care LLC, an Engineered Tissue Solutions (ETS) subsidiary focused on commercializing next generation wound care solutions, announced MIRRAGEN™ Advanced Wound Matrix was cleared by the United States Food and Drug Administration (FDA) for treatment of acute and chronic wounds. MIRRAGEN™ is a fully resorbable borate glass matrix comprised of fibers and beads proven to be highly effective in wound care management.

MIRRAGEN™ represents a breakthrough discovery for chronic and acute wound management due to its unique borate-based fiber matrix. MIRRAGEN™ is packed into wounds to manage and control wound fluids, while the resorbable matrix provides an environment for optimal wound healing. To learn more about the technology, click here. (more…)

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Think a Patient Has Rights? They Left.

Patient Rights

by Dr. Michael Miller

There are few absolutes in my universe. I know that my youngest daughter will gleefully and with full malice (but humorously presented) find something to torment me about every time I see her; referrals from family practice docs arrive well marinated in multiple antibiotics with nary a diagnosis in sight (save for the ubiquitous “infection”); and that regardless of what I recommend, offer, beg, plead, or cajole, that the patient has the complete and total power to make their decisions regarding their care and who provides it. Unless they are deemed by multiple authorities to be incapable of making a decision, until the appropriate paperwork or an emergency situation exists mandating immediate lifesaving action, the ball bounces squarely in their court…or so I thought. (more…)

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Jim Nabors Would Just Cry

jim nabors

by Dr. Michael Miller

For those of you not as familiar with the Hoosier State as you should be, I used to think it was essentially paradise. Jim Nabors of Gomer Pyle fame is our ubiquitous, tuneful icon with his always well-received “Back Home in Indiana” as a mantra to that source of pride.  Our former Governor “My Man” Mitch Daniels was a genius who, using a combination of intelligence, common sense and the persuasive powers of a midwest Svengali, created an economic model that our neighbors can only lust after. Our medicolegal climate is among the best in the US and well it should be. However, while there are some extraordinary caregivers and facilities here, a recent US News and World Report curiously showed that almost none of our hospitals made their “Best of” lists in any category. That is not to say there is bad care but to not have a single facility in an entire state even achieve an honorable mention gives one pause to reflect. The State newspapers were notoriously quiet on this concerning fact despite their trumpeting of who does what well, when and where. (more…)

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Condemning Patients to a Leap of Faith

leap of faith

by Dr. Michael Miller

I have several letters after my name.  The two that say “DO” indicate that I have the training of a physician and the requisite education and responsibilities that uphold those letters.  They should mean to patients that my ultimate goal is to offer (and provide when the fates allow) the entire spectrum of medical care referable to what I am good at and what they came to seek solace for.  Nothing less and if I keep my ego in check, certainly nothing more. Patients run the gamut of their perception of the medical field.  But like the old sales nemesis called “Bait and Switch”, what is offered on the sign all too often does not truly match what is seen on the shelves.  Arrogant people are that way because they are good at what they do and not afraid to tell others.  As a child, we are told to let others brag about us but failing to let people know what we can and can’t do is integral to our patients’ survival and our success.  The problem is that the glitz and glamour of being a healer all too often clouds our success.  Some time ago, I blogged about the pseudo-utilitarianism of all those so-called “Wound Certification” Exams.  At first blush, these seem to be the key to health, wealth, omniscience and outcomes equaled only by those wound care management companies. (more…)

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Help Me, Help Me, Help Me…next Tuesday

physicians

by Dr. Michael Miller

Health care providers are by nature an altruistic bunch.  I have the honor of interviewing potential entries to my beloved profession as part of the admissions process at the newest Osteopathic Medical School in Indiana, Marian University.  The process is unique in that it does not simply ask the age old questions of “Why you want to be a physician ?”, (“Because I want to do primary care in a rural area”).  No, our probing involves scenarios in which they have to look at a social situation, identify their thoughts, those of the opposing views and then cohesively demonstrate intelligence, confidence, logical thought processes and humanity…all in an 8 minute period repeated 7 times.  Their responses juxtaposed against what I see in my day to day always gives me pause to think about how the practice of medicine has been so perverted by the promotion of self abdication of responsibility.  The “let your government do it for you” mantras and newest politically correct definitions of disabled (encompassing everything from melancholia to dislike of red M and M’s) have resulted in a major paradigm shift in medicine.  Whereas, the hospitals once touted their ability to heal all manner of maladies, they now recognize their cost ineffectiveness, more detrimental than beneficial care (just check the nutritional parameters of anyone pre and post hospitalization) and the downright danger of going to one, unless you are a burgeoning superbug. (more…)

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Alternate universes – Einstein’s insanity

Wound Care

I remain absolutely amazed that there are so many people doing the same thing and yet doing it so completely different. Depending on where a patient’s wound care and orders originate from, the care I try to translate from that starting point is always a combination of dressing regimens worthy of computer code in their simplicity. The only thing usually missing is the diagnosis. It’s as though they come from an identical planet in an alternate universe.

The issue is that there is the complete dissociation of what is done for a given wound care problem in one practice setting versus another. Having stayed as far away from hospital-based wound care as possible, I continue to be amazed by hospital wound teams touting their expertise while using two to three times a day dressing changes and therapies that are the antithesis of any identifiable evidence. They actually expect entities receiving their cases (including home healthcare agencies, LTAC, skilled facilities, and others) to copy the identical care scenario regardless of their widely variable situations. In fact, the only constant is the patient and his or her condition. (more…)

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Crawford bags FDA clearance for wound dressing that will ‘save limbs’

Crawford Healthcare, one of the biggest makers of advanced wound-care products in the UK, has won clearance from US regulators for a medical dressing that it says will “save limbs”.

The product, called KerraCel AG, soaks up fluid and bacteria from nasty, oozing wounds and locks it away as a gel. It is also the only dressing of its kind to contain silver at a special concentration to kill all bacteria – even those resistant to antibiotics – that prevent chronic wounds, such as diabetic ulcers and pressure sores, from healing.

Read more at The Telegraph

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Management of Patients With Venous Leg Ulcers

It is well documented that the prevalence of venous leg ulcers (VLUs) is increasing, coinciding with an ageing population. Accurate global prevalence of VLUs is difficult to estimate due to the range of methodologies used in studies and accuracy of reporting.1 Venous ulceration is the most common type of leg ulceration and a significant clinical problem, affecting approximately 1% of the population and 3% of people over 80 years of age2 in westernised countries. Moreover, the global prevalence of VLUs is predicted to escalate dramatically, as people are living longer, often with multiple comorbidities. Recent figures on the prevalence of VLUs are based on a small number of studies, conducted in Western countries, and the evidence is weak. However, it is estimated that 93% of VLUs will heal in 12 months, and 7% remain unhealed after five years.3 Furthermore, the recurrence rate within 3 months after wound closure is as high as 70%.4-6 Thus, cost-effective adjunct evidence-based treatment strategies and services are needed to help prevent these ulcers, facilitate healing when they occur and prevent recurrence.

The impact of a VLU represents social, personal, financial and psychological costs on the individual and further economic drain on the health-care system. This brings the challenge of providing a standardised leg ulcer service which delivers evidence-based treatment for the patient and their ulcer. It is recognised there are variations in practice and barriers preventing the implementation of best practice. There are patients not receiving appropriate and timely treatment in the initial development of VLUs, effective management of their VLU and preventing recurrence once the VLU has healed.

Health-care professionals (HCPs) and organisations must have confidence in the development process of clinical practice guidelines and have ownership of these guidelines to ensure those of the highest quality guide their practice. These systematic judgments can assist in policy development, and decision making, improve communication, reduce errors and improve patient outcomes.

Read more at Journal of Wound Care

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Reduction of 50% in Diabetic Foot Ulcers With Stem Cells

Diabetic Foot Ulcers

MUNICH — Local injection of mesenchymal stem cells derived from autologous bone marrow shows promise in healing recalcitrant neuropathic diabetic foot ulcers, a novel study from Egypt shows.

Presenting the results at the European Association for the Study of Diabetes (EASD) 2016 Annual Meeting, Ahmed Albehairy, MD, from Mansoura University, Egypt, said: “In patients who received the mesenchymal stem cells, ulcer reduction was found to be significantly higher compared with patients on conventional treatment after both 6 weeks and 12 weeks of follow-up. This is despite the fact that initial ulcer size was larger in the stem-cell–treated group.” (more…)

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