You Are Here

Opioid Treatment and Chronic Wound Healing

Opioid Treatment and Chronic Wound Healing

While opioids are routinely prescribed for painful and chronic wounds, the effects of the medications are not well described in literature. Past studies suggest that stimulation of mu-opiate receptors on keratinocytes may induce transforming growth factor-beta (TGF-beta) and cytokeratin 16 (CK16), which are molecules that appear in wound healing environments. However, other studies suggest opioids may impede immune activation and negatively affect healing. This longitudinal observational study sought to elucidate the effect of opioids on healing of wounds in the Wound Healing and Etiology (WE-HEAL) Study, a repository of 450 patients. Parameters such as pain score, longitudinal opioid exposure, and total wound surface area (tWSA) were investigated. (more…)

Read More
Do NOT follow this link or you will be banned from the site!

Wound Care is Important. Please spread the word :)

RSS5k
Follow by Email102k
Facebook4k
Facebook