Guidelines for optimal off-loading to prevent diabetic foot ulcers
“The management of diabetic foot ulcers through optimal off-loading,” published in the Journal of the American Podiatric Medical Association, presents consensus guidelines and states the “evidence is clear” that off-loading increases healing of diabetic foot ulcers.
The article calls for increased use of off-loading and notes that “current evidence favors the use of nonremovable casts or fixed ankle walking braces as optimum off-loading modalities.” The authors reviewed about 90 studies. (more…)
Hansen’s disease, also called leprosy, is treatable today – and that’s partly thanks to a curious tree and the work of a pioneering young scientist in the 1920s. Centuries prior to her discovery, sufferers had no remedy for leprosy’s debilitating symptoms or its social stigma.
This young scientist, Alice Ball, laid fundamental groundwork for the first effective leprosy treatment globally. But her legacy still prompts conversations about the marginalization of women and people of color in science today.
Alice Augusta Ball, born in Seattle, Washington, in 1892, became the first woman and first African American to earn a master’s degree in science from the College of Hawaii in 1915, after completing her studies in pharmaceutical chemistry the year prior.
After she finished her master’s degree, the college hired her as a research chemist and instructor, and she became the first African American with that title in the chemistry department.
Doctors now understand that leprosy, also called Hansen’s disease, is minimally contagious. But in 1865, the fear and stigma associated with leprosy led authorities in Hawaii to implement a mandatory segregation policy, which ultimately isolated those with the disease on a remote peninsula on the island of Molokai. In 1910, over 600 leprosy sufferers were living in Molokai.
Doctors had attempted to use nearly every remedy imaginable to treat leprosy, even experimenting with dangerous substances such as arsenicand strychnine. But the lone consistently effective treatment was chaulmoogra oil.
Chaulmoogra oil is derived from the seeds of the chaulmoogra tree. Health practitioners in India and Burma had been using this oil for centuries as a treatment for various skin diseases. But there were limitations with the treatment, and it had only marginal effects on leprosy.
The oil is very thick and sticky, which makes it hard to rub into the skin. The drug is also notoriously bitter, and patients who ingested it would often start vomiting. Some physicians experimented with injections of the oil, but this produced painful pustules.
The Ball Method
If researchers could harness chaulmoogra’s curative potential without the nasty side effects, the tree’s seeds could revolutionize leprosy treatment. So, Hollmann turned to Ball. In a 1922 article, Hollmann documents how the 23-year-old Ball discovered how to chemically adapt chaulmoogra into an injection that had none of the side effects.
The Ball Method, as Hollmann called her discovery, transformed chaulmoogra oil into the most effective treatment for leprosy until the introduction of sulfones in the late 1940s.
In 1920, the Ball Method successfully treated 78 patients in Honolulu. A year later, it treated 94 more, with the Public Health Service noting that the morale of all the patients drastically improved. For the first time, there was hope for a cure.
Ball’s death meant she didn’t have the opportunity to publish her research. Arthur Dean, chair of the College of Hawaii’s chemistry department, took over the project.
Dean mass-produced the treatment and published a series of articles on chaulmoogra oil. He renamed Ball’s method the “Dean Method,” and he never credited Ball for her work.
Ball’s other colleagues did attempt to protect Ball’s legacy. A 1920 article in the Journal of the American Medical Association praises the Ball Method, while Hollmann clearly credits Ball in his own 1922 article.
Ball is described at length in a 1922 article in volume 15, issue 5, of Current History, an academic publication on international affairs. That feature is excerpted in a June 1941 issue of Carter G. Woodson’s “Negro History Bulletin,” referring to Ball’s achievement and untimely death.
Joseph Dutton, a well-regarded religious volunteer at the leprosy settlements on Molokai, further referenced Ball’s work in a 1932 memoir broadly published for a popular audience.
Historians such as Paul Wermager later prompted a modern reckoning with Ball’s poor treatment by Dean and others, ensuring that Ball received proper credit for her work. Following Wermager’s and others’ work, the University of Hawaii honored Ball in 2000 with a bronze plaque, affixed to the last remaining chaulmoogra tree on campus.
In 2019, the London School of Hygiene and Tropical Medicine added Ball’s name to the outside of its building. Ball’s story was even featured in a 2020 short film, “The Ball Method.”
The Ball Method represents both a scientific achievement and a history of marginalization. A young woman of color pioneered a medical treatment for a highly stigmatizing disease that disproportionately affected an already disenfranchised Indigenous population.
In 2022, then-Gov. David Ige declared Feb. 28 Alice Augusta Ball Day in Hawaii. It was only fitting that the ceremony took place on the Mānoa campus in the shade of the chaulmoogra tree.
Jitka Petrlova at Lund University, Sweden, together with Peter Bond’s team at the A*STAR Bioinformatics Institute, has discovered a strategy that the body uses to neutralize invading microbes. This finding is a critical development in fighting bacteria in skin wounds. Read more.
A study published online in The FASEB Journal delves into the mystifying fact that wounds in your mouth heal faster and more efficiently than wounds elsewhere. Until now, it was understood that saliva played a part in the wound healing process, though the extent of its role was unknown. The study examined the effects of salivary peptide histatin-1 on angiogenesis (blood vessel formation), which is critical to the efficiency of wound healing. Researchers found that histatin-1 promotes angiogenesis, as well as cell adhesion and migration. (more…)
Antibiotic overuse contributes to the problems of antibiotic resistance and healthcare acquired infections, such as Clostridium difficile. Antibiotic stewardship programs improve patient outcomes, reduce antimicrobial resistance, and save money. These programs are designed to ensure patients receive the right antibiotic, at the right dose, at the right time, and for the right duration. (more…)
Winning the battle of skin tears in an aging population
"Skin tears" may sound like a relatively minor event, but in reality, these injuries can have a significant impact on the quality of patients' lives in the form of pain, infection, and limited mobility.
The incidence of skin tears has been reported to be as high as 1.5 million annually, and with an aging population, this number is likely to go higher.
In this webinar, experts will explain how nurses can use an evidence-based approach -- including following practice guidelines to assess the wound and select the proper dressing -- for managing skin tears and minimizing their negative effects.
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Skin Damage Associated with Moisture and Pressure
• Identify how wounds are classified according to wound depth and etiology
• Describe the etiology of pressure injury and incontinence- associated skin damage (IAD)
• Understand evidenced-based protocols of care for prevention and management of IAD and pressure injuries
• Recognize and describe NPUAP-EPUAP Pressure Injury Classification System
• Understand appropriate ConvaTec products that can be used for prevention and treatment of IAD and pressure injuries
Wound Care Advisor eBooks are interactive digital tools full of insightful content, white papers and tutorials on trending topics that are assembled from the editorial staff along with supportive content provided by our marketing partners.
Accurate and considered wound assessment is essential to fulfill professional nursing requirements and ensure appropriate patient and wound management.
BY: NANCY MORGAN, RN, BSN, MBA, WOCN, WCC, CWCMS, DWC
Support surfaces are geared for managing our patients’ tissue load and redistributing it to prevent skin breakdown. There are three types of pressure redistribution mattresses available, classified as group 1, group 2, and group 3. Group 1 mattresses lack a power source and maintain a constant state of inflation. They include foam mattresses, gel mattresses, and air mattresses. Group 2 support surfaces, such as powered, low-air-loss, and alternating pressure mattresses use inflation and deflation to spread the tissue load over a large surface area. Group 3 mattresses include the air-fluidized mattress, a special type of powered mattress that provides the highest-pressure redistribution via a fluid-like medium created by forcing air through beads, as characterized by immersion and envelopment. (more…)
I remain absolutely amazed that there are so many people doing the same thing and yet doing it so completely different. Depending on where a patient’s wound care and orders originate from, the care I try to translate from that starting point is always a combination of dressing regimens worthy of computer code in their simplicity. The only thing usually missing is the diagnosis. It’s as though they come from an identical planet in an alternate universe.
The issue is that there is the complete dissociation of what is done for a given wound care problem in one practice setting versus another. Having stayed as far away from hospital-based wound care as possible, I continue to be amazed by hospital wound teams touting their expertise while using two to three times a day dressing changes and therapies that are the antithesis of any identifiable evidence. They actually expect entities receiving their cases (including home healthcare agencies, LTAC, skilled facilities, and others) to copy the identical care scenario regardless of their widely variable situations. In fact, the only constant is the patient and his or her condition. (more…)
Researchers have developed a new infection-blocking material made of peptide-containing nanofibers that works against antibiotic-resistant bacteria and could one day be incorporated into wound dressings (ACS Infect. Dis. 2017, DOI: 10.1021/acsinfecdis.6b00173).
The approach targets bacterial quorum sensing—a mode of chemical communication used by bacteria to detect other bacteria. When they sense that enough of their kind are present, they can mount an infectious attack.
Wound Care Advisor eBooks are interactive digital tools full of insightful content, white papers and tutorials on trending topics that are assembled from the editorial staff along with supportive content provided by our marketing partners.
Accurate and considered wound assessment is essential to fulfill professional nursing requirements and ensure appropriate patient and wound management.
The National Pressure Ulcer Advisory Panel (NPUAP) describes support surfaces as “specialized devices for pressure redistribution designed for management of tissue loads, microclimate, and/or other therapeutic functions.” These devices include specialized mattresses, mattress overlays, chair cushions, and pads used on transport stretchers, operating room (OR) tables, examination or procedure tables, and gurneys. Some support surfaces are part of an integrated bed system, which combines the bed frame and support surface into a single unit. (more…)